Space isn't designed for humans. Zero gravity affects us in many ways, changing how our mind works, our circulatory system, and even our nervous system and bones - until we return to Earth. If you dream of being an astronaut, expect changes due to weightlessness. These changes aren't unusual, but sometimes unexplainable. NASA and other agencies constantly study the effects of space on the human body as we plan to extend our stay in the universe. Read on to discover what happens to your body in orbit - it's not what you've seen in sci-fi movies.
About this list
- 1

Without gravity holding us down, things shift. This makes sense.The human brain appears to be one of those things.Researchers recently found the brain shifts upward while astronauts are in space. This protective fluid around it on Earth lessens at the top of the head. Most of it sits inside the brain's ventricles or cavities. This explains symptoms astronauts report, like head pressure and vision problems.
More tests are needed. We plan to send astronauts on longer missions in the future.
57 - 2

About 80% of astronauts returning to Earth report vision issues. Scientists now call this visual impairment and intracranial pressure syndrome.Visual impairment and intracranial pressure syndrome (VIIP).Scientists do not know what causes VIIP. Studying it on Earth is hard because replicating the situation is nearly impossible.
MRIs and retinal scans find VIIP. Exams show a space traveler's eye backs flatten, and the retinas push forward. Gravity's absence is a factor, but the exact mechanics remain unknown.
52 - 3

In space, no ozone layer blocks harmful rays. Astronauts face much more radiation, which hits the traveler's DNA. Short-term radiation exposure causes nausea, vomiting, and bloody diarrhea. Long-term exposure can kill; cancer is the main threat. Sterility and gene mutation, which pass to generations, are also risks.
The Space Radiation Analysis Group (SRAG) monitors astronauts 24/7 from Mission Control in Houston.Space Radiation Analysis GroupThe Space Radiation Analysis Group (SRAG) at Mission Control in Houston ensures their radiation exposure stays below acceptable limits.
50 - 4

Leaching minerals from bones raises blood calcium levels. Difficulty emptying the bladder, plus struggling to stay hydrated, makes space travelers prone to kidney stones.
According to NASA,NASA"Therapy options for this condition are severely limited in spacecraft." If you skip prevention, you face trouble. Kidney stones hurt badly. An anonymous patient reported stones just three months after birth were worse than labor.Urology AustinThe stones were worse than labor.
43 - 5

NASA used astronaut Scott Kelly and his twin brother Mark, who retired as an astronaut, to compare how space affects the body in the "Twin Study." Mark stayed on Earth, but Scott lived on the International Space Station for almost a year. After returning, NASA studied the twins and found Scott's time in space switched genes "on and off" through methylation.
Dr. Chris Mason discusses how space travel switches genes on and off in 'Gross Things In Space'.Dr. Chris Mason, of Weill Cornell Medicine and a principal researcher in the study, said:
The human body explodes like fireworks when it enters space. This study showed thousands of genes change how they turn on and off. Astronauts change gene activity when they enter space, and some activity lasts briefly after they return to Earth.
42 - 6

Your upper body, especially your head and face, swells in space. Your legs get thinner. A fluid shift causes what is called "Microgravity causes your head and face to swell, according to 'Gross Things In Space'.." You look like a bodybuilder who doesn't know what "leg day" means.
Lack of gravity causes this. Space has no gravity to pull things down. Your fluids naturally rise to the top of your body. Blocked or bloody noses can happen, but everything returns to normal on Earth.
32 - 7

Muscles help you move on Earth against gravity. Without gravity, muscles have nothing to fight against. The longer you stay out there, the less they work. In space,Your muscles weaken in space, listed in 'Gross Things In Space'.by about 20%, increasing with time spent without gravity.
Astronauts fight this with exercise. They strap themselves to weights on stationary bikes or use gear built for weightless space. This also helps bone loss and mental health. Astronauts exercise about two hours daily in space.
31 - 8

In space, astronauts lose at least 14% of their bone strength and face a higher risk of fractures later. Some astronauts lose a massive 30% of their bone mass. This puts them on par with postmenopausal women with osteoporosis, even at their physical peak.
Earth's gravity causes a specific effect on bone strength.Mechanical load affects bone strength." which helps bones keep the right density to support the body. That does not exist in space.
30 - 9

Astronauts need peak physical condition to enter space, but they do not stay that way. Aside from the effects of no gravity, their immune systems feel the change too. Brian Crucian, aNASA biological studies and immunology expert discusses how space weakens the immune system.The person who led an immune system study on astronauts said this:
Radiation, microbes, stress, microgravity, altered sleep cycles, and isolation all affect crew member immune systems. These factors increase infection, hypersensitivity, or autoimmune issues for exploration astronauts if the situation lasts longer in deep space.
Scientists found that blood samples before, during, and after spaceflights showed immune cell distribution stayed similar, but they did not react to threats the same way. This mirrors an autoimmune disease. Astronauts show "asymptomatic viral shedding," meaning dormant viruses wake up. Some astronauts see increased allergies and rashes, but immune cell changes do not show serious side effects.
21 - 10

Space is amazing and awe-inspiring. It is also very isolating. Astronauts report depression, hallucinations, and extreme stress over the years. Being confined in small spaces with the same people doing repetitive tasks also pushes people to their limits.
Mark Shelhamer.Chief Scientist at NASA's Human Research Program explained.
Astronauts are highly motivated, trained people. Human nature causes them to hit a phase of low motivation or crewmate issues. This is something to recognize, but mission design must allow for it.
NASA maintains psychological testing and support because the agency plans a Mars colony someday.
15 - 11

Astronauts eat special food for space travel. However, they also take vitamins because they risk becoming nutrient deficient quickly. Astronauts lose vitamin D once in space saysJoshua Byerly.A Johnson Space Center spokesman said:
We give crews vitamin D supplements. The food system lacks vitamin D sources. Spacecraft also block ultraviolet light, which is how the body makes vitamin D.
Vitamin D helps prevent bone and muscle loss, a certainty due to microgravity.Calcium and vitamin K deficiencies.These deficiencies have also been reported.
9 - 12

If boats cause motion sickness, you are not a good choice for space. The shift between gravity fields causes many side effects, most of which lead directly toMotion sickness.. NASA states: "It affects your spatial orientation, head-eye and hand-eye coordination, balance, and locomotion."
7 - 13

Space makes you taller, at least until you return to Earth. Lack of gravity causes this. Your spine acts like a spring; gravity pushes it down or compresses it. Without gravity, the opposite happens. Dr. Sudhakar Rajulu, a researcher at Johnson Space Center's Habitability and Environmental Factors, says elongation only affects the spine, not the limbs, because of its compressible discs.
The spine curves naturally on Earth. In space, it lengthens. Gravity pulls things down, so discs stay pressed. Space allows discs to hold more spinal fluid, creating more space between each vertebra.
6 - 14

Without Earth's 24/7 day and night cycle, it should be no surprise thatSleep changes in spaceBecause of microgravity, you must strap yourself in to sleep. Thinking about curling your knees into a fetal position? Forget it. Zero gravity stretches you out; you won't stay that way even if you fall asleep that way.
Microgravity helps you relax. Floating lets you avoid a bad mattress, so you skip morning back kinks.-13
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